The main purpose of topical treatment is to reduce inflammation, relieve pain, and promote ulcer healing. There are many treatment methods, which are selected according to the condition:
1. Gargle: 0.25% chlortetracycline solution, 1:5000 chlorhexidine chlorhexidine solution, 1:5000 potassium permanganate solution, 1:5000 nitrofurazone solution, etc.
2. Lozenges: Dumifen lozenges, lysozyme lozenges, and chlorhexidine lozenges.
3. Powder: Bingbo powder, tin powder, Qingdai powder, Yangyinshengji powder, etc. are the main medicines for treating oral ulcers in traditional Chinese medicine. In addition, compound betamethasone spread also has anti-inflammatory, analgesic, and promoting ulcer healing effects.
4. Drug film: The matrix contains antibiotics and cortisone and other drugs. Sticking to the ulcer can relieve pain, protect the ulcer surface and promote healing.
5. Analgesics: 0.5%～1% procaine solution, 0.5%～1% dyclonine solution, 0.5%～1% dicaine solution, apply on the ulcer surface, 2 times in a row, use Temporarily relieve pain before eating.
6. Burning method: suitable for those with few ulcers, small area and intermittent period. The method is to first apply 2% dicaine to surface anesthesia, isolate the moisture, dry the ulcer surface, and dip a small cotton ball with an area smaller than the ulcer surface 10% silver nitrate solution or 50% trinitroacetic acid tincture or iodine phenol solution. Put it on the ulcer surface until the surface turns white. These drugs can precipitate proteins on the ulcer surface to form a film to protect the ulcer surface and promote healing.
7. Partial closure: suitable for severe recurrent aphthous ulcers. Add 0.5-1 ml of 2.5% prednisolone acetate suspension to 1 ml of 1% procaine solution and inject it into the lower tissue of the ulcer, 1-2 times a week, for a total of 2-4 times. Has accelerated ulcer healing.
8. Laser treatment: Irradiation with helium-neon laser can activate the mucosal regeneration process, reduce the inflammatory response, and promote healing.
systemic therapy
1. Immunosuppressive agents: If it can be determined as an autoimmune disease by examination, the use of immunosuppressive agents has obvious curative effect. The most commonly used drug is prednisone (prednisone). To prevent the spread of infection, antibiotics should be added. For severe Behçet syndrome, hydrocortisone or dexamethasone and tetracycline should be given, and it should be disabled or used with caution in patients with gastric ulcer, diabetes, and active pulmonary tuberculosis.
2. Immunomodulators and enhancers:
(1) Levamisole is used for those who need to enhance cellular immunity.
(2) gamma globulin is suitable for those with impaired humoral immunity. Not suitable for long-term use.
(3) Transfer factor is suitable for those with reduced or defective cellular immune function.
(4) Vitamins Vitamins can maintain normal metabolic function and promote the healing of lesions. When the ulcer occurs, vitamin C 0.1-0.2g is given, 3 times a day, and vitamin B complex is 1 tablet each time, 3 times a day.
(5) Female hormones Women whose onset is related to the menstrual cycle can use estrogen and diethylstilbestrol with caution.
(6) If the serum zinc content of the trace element decreases, the condition improves after zinc supplementation, and 1% zinc sulfate syrup or zinc sulfate tablets can be used.
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