Studies have shown that titanium particles can appear in inflamed tissue around dental implants. But a new study published in Communications Medicine shows that titanium particles were found in all implants examined, regardless of whether there were signs of inflammation.
Tord Berglundh, senior professor of periodontology at Sahlgrenska Academy at the University of Gothenburg, told Medical Xpress that titanium is a “well-studied material that has been used for decades.”
“It is biocompatible and safe, but our findings suggest that we need to better understand what happens to these particles over time. Do they stay in the tissue, or do they spread to other parts of the body?” Berglundh said.
The study by the University of Gothenburg and Uppsala University analyzed human soft tissue samples taken from implant sites with and without peri-implantitis and found 14 genes that may be affected by these particles.
“But it is still unclear whether these particles influence the local immune response or whether differences in gene expression reflect inter-individual differences in inflammatory conditions,” says periodontist Carlotta Dionigi, researcher at the Department of Periodontology at Saargar Academy, University of Gothenburg.
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