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NOBS Toothpaste Tablets Match Fluoride in Effectiveness

Cecilia by Cecilia
05/17/2025
in teeth whitening
NOBS Toothpaste Tablets Match Fluoride in Effectiveness

In a just-released study, NOBS by biöm, in partnership with the University of Texas Department of General Dentistry, conducted a comprehensive study of its fluoride-free toothpaste tablets, showing that a toothpaste tablet containing 5% nanohydroxyapatite (NOBS Toothpaste Tablets) is as effective as a NaF (fluoride-based) toothpaste containing 1100 ppm fluoride in preventing tooth demineralization.

Oral hygiene brand NOBS by biöm was founded by a group of dental professionals who were put off by the shortcomings of traditional oral care products. The brand partnered with the University of Texas Department of Dentistry to conduct an independent study, published in the MDPI Journal of Dentistry. The results showed that the company’s toothpaste tablets are as effective as fluoride toothpaste in preventing tooth demineralization.

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In 4 randomly assigned groups, NOBS (leading fluoride toothpaste brand), placebo, and no treatment, NOBS toothpaste tablets provided comparable protection to the leading US fluoride toothpaste, reduced enamel damage in half compared to unbrushed teeth, and were more than twice as effective as the placebo tablets.

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The seven-day peer-reviewed study proves that safe ingredients provide strong cavity protection without added fluoride, researchers said. In a press release announcing the findings, Biöm said it has invested heavily in product transparency to back up its claims, share unfiltered results, and let the facts speak for themselves.

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Research shows that NOBS Toothpaste Tablets:

Comparable to the protection of the #1 fluoride toothpaste in the U.S.

50% less enamel damage (compared to no brushing)

More than twice as effective as a placebo tablet

Researchers at the University of Texas put NOBS Toothpaste Tablets through one of the most rigorous lab simulation tests ever

Tested on:

Real teeth

Bacteria that cause tooth decay

Sugar intake (3 times daily)

Four treatments tested: NOBS Tablets, fluoride toothpaste, placebo, no brushing at all
NOBS by biöm Toothpaste Tablets contain 5% clinical grade nanohydroxyapatite (to strengthen enamel), xylitol (to fight bacteria), zinc citrate (to control plaque), and no artificial sweeteners.

The study authors wrote in their conclusion: “Within the scope of this in vitro study, the tested toothpaste tablet containing 5% nanohydroxyapatite (Biöm ® NOBS™ toothpaste tablet) showed a significant ability to inhibit tooth surface demineralization, which is comparable to a toothpaste containing 1100 ppm fluoride.

Thus, the nanohydroxyapatite toothpaste tablet can be an effective alternative to over-the-counter standard fluoride toothpaste. This further demonstrates that the tested toothpaste tablet can inhibit the development of caries in the presence of high levels of dental plaque.”

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